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The core sequence is based on a consensus of gene content derived from five publicly available IncX1 plasmid sequences, each consisting of a mostly conserved plasmid backbone, alongside accessory genetic loads of varying sizes ( fig. 1 ). Apart from the consensus IncX1 gene content, pOLA52 carries a genetic load of approximately 22 kb.


Chrysostomou V, Rezania F, Trounce IA, cheap silagra online Crowston JG (2013) Oxidative stress and mitochondrial dysfunction in glaucoma. Yusim K, Peeters M, Pybus OG, Bhattacharya T, Delaporte E, et al. (2001) Using human immunodeficiency virus type 1 sequences to infer historical features of the acquired immune deficiency syndrome epidemic and human immunodeficiency virus evolution.

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Mary Ann Handel and Carol Bult for comments on this manuscript. Figure 5 Leflunomide induces aryl hydrocarbon receptor dependent expression of CYP1A1 in zebrafish.

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