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Our studies highlight a previously unexplored link between innate immune signaling and activation of oncogenic pathways, which may be targeted to prevent or treat CRC.
The CTRL and BAT samples were pooled in 2 distinct groups.
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Measurement of autofluorescence, ROS, organellar contents, and mitochondrial membrane potential For quantitation of autofluorescence, the cells were washed with PBS, trypsinized, collected in PBS, and analyzed on a FACSCaliber (Beckton Dickson). References Hutin Y, Nasrullah M, Easterbrook P, et al.
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Importantly, absolute entropy values are not relevant as they depend on image resolution as well as on the size of the Gaussian kernel used into convolution.
Additional inas regardsmation on the distribution of the samples to the different research groups is reported in Table S2.
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Haxby JV, Hoffman EA, Gobbini M I (2000) The distributed human neural system on face perception.
Edwards NC, Steeds RP, Ferro CJ, Townend JN (2006) The treatment of coronary artery disease in patients with chronic kidney disease. QJM.